Connect with others who understand.

sign up log in
About MyLupusTeam
Real members of MyLupusTeam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.

Has Anyone With SLE And Lupus Nephritis Who Was Treated With Cytoxan Been Able To Have Children?

Has Anyone With SLE And Lupus Nephritis Who Was Treated With Cytoxan Been Able To Have Children?

I would love some "real world" advice form those who have been through this as opposed to physicians telling me childbirth "isn't a good idea" with no evidence to back it up even though I have been in remission for over 3 years and and am doing great clinically with GFR of 70, Creatinine of 0.7- 1.0, ANA of 10 and dsDNA of 1:40- 1:160. Thank you in advance!

A MyLupusTeam Member said:

My lupus symptoms started with the birth of my 1st child (all my pregnancies were very very difficult),I had symptoms again after my 2nd child. My 3rd child sent my lupus and fibro through the roof....and I was finally diagnosed. I have had nephritis but never needed cytoxan. But I haven been on methotrexate which can cause severely abnormal pregnancies with a high risk of birth defects. Maybe that is the case with th cytoxan? Also, lupies naturally have a higher risk of miscarriage or severe flares during and after pregnancy. I would love to have 1 more little one but the flare I had after my 3rd almost killed me (its gotten worse with each birth ). I would look up the side effects for all of your meds...and talk to your pharmacist....hth

edited, originally posted about 7 years ago
A MyLupusTeam Member said:

I had 6 monthly treatments of cytoxan when I was 22 (2001). They warned me that it could affect my fertility. Fast forward a few years and I was a newlywed wanting a family. It took longer than expected, but I now have two healthy boys age 5 & 9. I had one miscarriage before either of them were born and it took about a year of various fertility treatments to get pregnant with my second, but no one could really tell me if that was due to the cytoxan or the lupus itself or if it was due to something else completely. Best of luck to you. Both of my pregnancies were considered high-risk, but the were both free of complications and my lupus numbers were great during both. Be careful after baby is born...keep a close eye on numbers until your hormones settle down. I flared after both pregnancies. the first time it completely caught me off guard, the second time I was ready for it and caught things much earlier on!

posted over 5 years ago
A MyLupusTeam Member said:

I had 6 monthly treatments of cytoxan when I was 22 (2001). They warned me that it could affect my fertility. Fast forward a few years and I was a newlywed wanting a family. It took longer than expected, but I now have two healthy boys age 5 & 9. I had one miscarriage before either of them were born and it took about a year of various fertility treatments to get pregnant with my second, but no one could really tell me if that was due to the cytoxan or the lupus itself or if it was due to something else completely. Best of luck to you. Both of my pregnancies were considered high-risk, but the were both free of complications and my lupus numbers were great during both. Be careful after baby is born...keep a close eye on numbers until your hormones settle down. I flared after both pregnancies. the first time it completely caught me off guard, the second time I was ready for it and caught things much earlier on!

posted over 5 years ago
A MyLupusTeam Member said:

Before I was put on cytoxan, I have had a partial hysterectomy several years before. My ovaries were intact. My doctor asked me if I was pregnant or planned on having kids later on, because the cytoxan would fry my ovaries.

edited, originally posted over 6 years ago
A MyLupusTeam Member said:

honestly everyone is different in this. some people feel great during pregnancy then after they are super sick and i mean SUPER sick. Some people die (one of the main things my family fears) and some people do just fine. some people are fine but their kids are born with all sorts of illness and things. some people are sick through out and their kids come out absolutely fine. It really all depends its hard to say yes this is good or no this will not work out. I will say however I really do wish you the best. As far as me having first hand experience I cant say I do and if I ever want kids in my life I plan to adopt. My cousin did have a little boy and he is perfect. she was very happy her whole pregnancy but after she gave birth she was hospitalized all the time. she just recently got surgery to remove a tumor on her liver. Shes doing fine now still little flares here and there but she works full time and takes care of her son. She doesnt regret having her son even if she was really sick for a while. He is her life. Again I wish you the best of luck this is always a tough subject for all of us here.

posted about 7 years ago
Already a Member? Log in