Connect with others who understand.

sign up log in
About MyLupusTeam
Real members of MyLupusTeam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.

Methotrexate & Weight Gain??

Methotrexate & Weight Gain??

Taking methotrexate injections, Cymbalta and folic acid on Friday's and today finally feeling less tired. But since being on the methotrexate I have gained a substantial amount of weight. Can anyone relate to this experience? Might I be having a reaction to my kidneys? I read a little about that.

A MyLupusTeam Member said:

Morning,when they put me on steroids 5mgs,I gained about 20 pounds and I have been a healthy eater for a long time. I had hard time dealing with it but after writing about what was more important having less pain and some energy orbiting bigger clothes. I prayed for acceptance and it took me awhile to be ok with it. But I get ulcers in my stomach and the steroids makes them worse. So I was going to go off completely cause the pain from the ulcers I found to be unbearable. So I went to 3 mg of steroids and my stomach got better but I could tell the difference I had more pain and had more fatigue. I really didn't think that 2mg would make that much of a difference. I started actupture and boy what a difference we change my foods plus did colon actupture and she added a couple of supplements and I started during this shakes.well I have had server IBS-C for over 12years myriad doc I love but he was like the only think left is to remove your colon and that not to say that's go to work so I just brought bigger pants and would have to go to the Hosipal to get clean out if I did go to the bathroom by 3 weeks. After couple of weeks of working with my Acupuncturist I have been going to the bathroom almost every day, no more being bloated. So between going off 2mgs of steroids and going to the bath and changeing my food I have lost like 25 pounds. You know I will do anything to feel better that is a suggest threw my doctors weather I gain weigh . I just want energy back and have my pain lighten up. I don't want to be on tons of pain meds. So just remember if it makes you feel better and the side effects aren't to bad, I would stay on it. Sorry didn't mean to go on so much. Thanks guys for being here for me and I pray for all of us. I believe gods something coming for us, don't know when but it's coming. Have a good day

posted about 6 years ago
A MyLupusTeam Member said:

I am on lyrica 125 mg x 2 day, plaquenil, prednisone, and cymbalta 120mg for 2 months and i have gained 6 lbs in one month. No bueno....

posted about 6 years ago
A MyLupusTeam Member said:

I never been on that medication before but I am on prednisone and many others I gained more than 40 pounds in a short period of time. I am still in pain and have major breathing issues and chest pains especially with my heart and Lungs. I take my lupus medication and I am on blood thinners. I hate where I am at with my health but everyone on here gives me hope.

posted almost 2 years ago
A MyLupusTeam Member said:

I'm right with ya I've gained 20 lbs in 6 months & my kidneys r bad too plus I'm diabetic too this is scarring me I hurt all the time so I feel your pain if any solutions please let me know I'm praying for us !

posted almost 4 years ago
A MyLupusTeam Member said:

I have gained almost 20 kg since 2007 when i went on it. However, without it I would not manage the pain. I am on the tablets and take folic acid every day except once a week when I take the methotrexate tablets

posted over 6 years ago
Already a Member? Log in