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Hi, What Is The Difference Between ANA Direct And ANA Tests?

Hi, What Is The Difference Between ANA Direct And ANA Tests?

A MyLupusTeam Member said:

My new primary care doctor ordered the test because I have the butterfly rash and I have been having a lot of joint pain in my legs, wrists, and fingers.

posted almost 2 years ago
A MyLupusTeam Member said:

I thought I answered this but it didn't post. There are 3 ANA tests, or levels of ANA tests. 1) If an autoimmune disease is suspected, ANA test that brings back a titer and a pattern is done. 2) If a rheumatic autoimmune is suspected, then another ANA IFA is usually done, and that one repeats the above but also looks for 11 antibodies to pinpoint to specific disease. 3) If cascade of 11 antibodies is negative or insufficient, then a third option is to test for other antibodies, i.e., rheumatoid factor (RF) is done. It is usually done in that order since if the 1st ANA is negative, no need to do a more comprehensive 2nd ANA and so forth. Short version but hope it's helpful.

edited, originally posted almost 2 years ago
A MyLupusTeam Member said:

I would feel reassured based on these test results that it is not lupus but continue to explore with your pcp to find out what is. Best of luck!

edited, originally posted almost 2 years ago
A MyLupusTeam Member said:

Other than low Vit D, other values are negative, so looks good. Direct ANA might have shown low titer of antinuclear antibodies. That can happen with a lot of healthy ppl and about 50% of elderly are positive. ANA IFA is negative and none of the 9 lupus markers tested are positive. I think this is reassuring as far as ruling lupus out at this point. Can I ask which Dr ordered tests and why? That is important info. Also, did you have a chance to go over your results with him/her?

edited, originally posted almost 2 years ago
A MyLupusTeam Member said:

Sana. Thank you. The results i attached in a picture .This is so confusing to me. I don't have any more tests.

posted almost 2 years ago
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