Good at first. In the middle of week I felt tired

I agree. I totally feel drained for a day or two after the infusion, but in the grand scheme of things; it’s so worth it.

I have been on Benlysta infusions every four weeks for about a year now. When I first started the infusions they were like a miracle drug! I actually had the energy to play with my son after work or to clean up the house! However, i do feel that over time the benefits of the treatment have seemed to decrease, though, im sure the Benlysta still helps a lot. Also, I am not sure if it is so much a tolerance that i might have built up to the infusions, but maybe my Lupus, MCTD, etc might be possibly getting worse. I will say that to this day, i still sometimes feel WIPED after an infusion for about a day, but that is better than feeling that way all month! I do feel Benlysta is a great treatment over all. I hope this helps in some way! Good luck!

I take Benlysta infusions. The first time I had it I got really tired and nauseous. During the first week, I was really fatigued and had decreased appetite.
The next month I was fine. Your doctor should be giving you a Tylenol, Benadryl, and an anti-nausea medication before they give you the infusion.