Hello -- I am going for my 3rd infusion of Saphnelo today. The first 2 times left me really tired the next day. Sometimes I've wondered: is it worth the cost? I tried the at-home Benlysta shots for about 5 months a few years ago and didn't notice any improvement. My goal is to give this Saphnelo more of a chance. Sometimes my symptoms seem to be improving and then I'll end up in bed for a day or two and think it was all in my head. Overall though I would say my symptoms are less than they were 6 months ago. Praying for you both as you and your healthcare team figure out what's best for you.

Update: After being on Saphnello for six months and only feeling worse, my Dr. stopped it and put me back on Benlysta. After taking it for three months I started feeling better and am still feeling better at six months. Maybe my body just needed a break from Benlysta to work again.

Thank you! I hope you feel better!

Thank you for your answer! Sometimes I think I notice that I'm feeling better but not in a big way yet. In two weeks it'll be three months since I started it. Maybe it's too soon to tell. Best of luck!🙂

So sorry to hear that! I hope you’re feeling better very soon!