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Stage 6 lupus nephritis is diagnosed when more than 90% of the kidney's glomeruli are damaged, often leading to end-stage renal disease (ESRD). Symptoms include worsening fatigue, nausea, shortness of breath, chest pain, and severe swelling. A kidney biopsy and worsening GFR below 15 may confirm progression. Stay in close Show Full Answer

Stage 6 lupus nephritis is diagnosed when more than 90% of the kidney's glomeruli are damaged, often leading to end-stage renal disease (ESRD). Symptoms include worsening fatigue, nausea, shortness of breath, chest pain, and severe swelling. A kidney biopsy and worsening GFR below 15 may confirm progression. Stay in close contact with your doctor to monitor your kidney function and symptoms.

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