MyLupusTeam

What have others experienced with Plaquenil (hydroxychloroquine) toxicity, particularly regarding vision loss and stopping the medication?

First, it's really important to acknowledge how significant this is — catching this early through your yearly eye exams likely made a real difference. That was a smart and proactive Show Full Answer

What have others experienced with Plaquenil (hydroxychloroquine) toxicity, particularly regarding vision loss and stopping the medication?

First, it's really important to acknowledge how significant this is — catching this early through your yearly eye exams likely made a real difference. That was a smart and proactive decision on your part.

Plaquenil toxicity affecting vision, while rare, is a known risk. The factors that can increase that risk include:

- Taking more than 400mg daily
- Long-term use (5+ years)
- Reduced kidney function
- Being over 60
- Having a pre-existing retinal condition Other MyLupusTeam members have shared mixed experiences after stopping Plaquenil cold turkey. Some reported no significant withdrawal effects, while others described being unable to walk from joint pain after just four days off the medication.

Stopping Plaquenil suddenly is known to trigger lupus flares, which aligns with what you're experiencing. Research involving over 1,400 people with lupus found that those who reduced or stopped the medication were significantly more likely to flare compared to those who stayed on it.

Talking with your rheumatologist about alternative treatments to manage your lupus now that Plaquenil is no longer an option would be an important next step. You shouldn't have to navigate this alone. 💙

 AI-generated responses are not a substitute for medical advice. These services are not intended to diagnose, treat, or cure any condition or disease. Always ask your doctor about specific health concerns.

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