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A MyLupusTeam Member asked a question 💭
Detroit, MI
June 14
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MyLupusTeam

Can hydroxychloroquine (Plaquenil) cause diarrhea? Yes, it can — and it's one of the more commonly reported digestive side effects of this medication.

Other gastrointestinal side effects that can come along with it include:

- Nausea
- Upset stomach or abdominal cramps
- Vomiting
- Loss of appetite

The good news is that these Show Full Answer

Can hydroxychloroquine (Plaquenil) cause diarrhea? Yes, it can — and it's one of the more commonly reported digestive side effects of this medication.

Other gastrointestinal side effects that can come along with it include:

- Nausea
- Upset stomach or abdominal cramps
- Vomiting
- Loss of appetite

The good news is that these symptoms often settle down on their own as the body adjusts to the medication. A few tips that may help ease stomach troubles:

- Take hydroxychloroquine with food or milk — this is one of the simplest ways to reduce stomach upset
- Stay well hydrated — diarrhea can lead to dehydration, so drinking plenty of water is important
- Don't skip meals when taking the medication

If diarrhea persists or becomes severe, it's worth reaching out to a doctor, as prolonged symptoms can lead to unwanted weight loss and appetite changes.

June 14

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