It sounds like you're asking about Imuran (azathioprine) — a common immunosuppressant used to treat lupus, especially when other treatments haven't worked well enough.
For many people, it's fairly well-tolerated, but it does come with some potential side effects worth knowing about:
- Nausea or stomach upset — often the most Show Full Answer
It sounds like you're asking about Imuran (azathioprine) — a common immunosuppressant used to treat lupus, especially when other treatments haven't worked well enough.
For many people, it's fairly well-tolerated, but it does come with some potential side effects worth knowing about:
- Nausea or stomach upset — often the most common complaint, especially early on
- Unintended weight loss — some people notice this, particularly those who previously gained weight from steroids
- Increased infection risk — since it suppresses the immune system
- Fatigue — which can overlap with lupus symptoms itself
The good news is that many MyLupusTeam members have found that once Imuran starts working, they actually feel *better* overall — with less pain and inflammation, which can make it easier to stay active.
That said, everyone responds differently. Some people tolerate it with minimal issues, while others find the side effects harder to manage.
It's always worth having an open conversation with your doctor about what to watch for and when to call them — especially if you notice significant weight changes, signs of infection, or unusual fatigue.
AI-generated responses are not a substitute for medical advice. These services are not intended to
diagnose, treat, or cure any condition or disease. Always ask your doctor about specific health concerns.
Does Azathioprine Cause Weight Loss?
July 14
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