I have been on it for four months and if I take it with a glass of milk, I don't have any pain.

Been on all kinds of meds since I was 10, imuran included. Have sle. The only thing that has worked for me with little to no side affects is cellcept.

I took it for over a year with no problems. It did really help me for a year but then started to have frequent flares again, so recently switched to CellCept. I really did like the Imuran though.

I've taken it for about 2 years. No side effects. I am now on methotrexate injections.

Thanks so much for all of your input. I called the Dr. a few days ago and expressed my concerns about the side effects and much to my surprise he took my call. After a lengthily conversation I agreed to take it. So far no side effects. Fingers crossed I have nothing but good results. Again, thanks for sharing!