When my Rheumatologist said that we went to Imuran, andd Immunosuppressive meds (chemo meds) , and various forms of Methotrexate. I ended up having reactions to all. Only thing we can use is rest, rest, and rest some more. Prednisone at different
levels according to any organ involvement , and a continuous 2.5 maintenance dose, along with Plaquenil twice a day. I wish you all the best! We are all unique. May your Physician find what works best for you.

Its just different meds.I had methotrexate and couldn t tolerate it so was given an immune suppresant.Not a big deal but I feel lik a million bucks.Still have pain etc but i feel better.

prednisone is bad makes you gain weight and that can cause issues with lupus.be careful some doctors cant be trusted .

Thankyou so much ...hugs to you xx

Big guns is usually imuran. There are some good infusion therapies. Benlysta is a new infusion therapy. It is the only drug developed specifically developed for lupus to attack the antibodies. I've been on and off of it since 2012. I was doing the clinical trial. I will say I have a lot of the side effects which I hate but a lot of people don't. I think I get them because my gastric system is already so messed up so I wouldn't steer you away from trying it. I would recommend that if you get nausea with the infusion treatment have them give you zofran with your treatment, it really helps. I tried methotrexate which really helped with pain but I had horrible mouth and nose sores so they had to switch me to imuran. Sending you hugs. Hope you feel better soon.