I’ve been on Benlysta infusions for almost three years. It helps with fatigue and joint pain. Very few people, less than 16%, get nausea. That’s my one and only side effect. I use ginger and an anti nausea medication when I feel yucky. Good luck 🍀

You have to take it for longer than 6 months to see a difference. I was in a lot of pain the first year. But we are all different ❤️

I took about 4 infusions. I had no bad effects!

I have been taking the self injections for 8 months and definitely see an improvement! My rheumy says that we have a year to see continued improvement, so I'm very hopeful that things will get better. I take it with 25mg of MTX, spike with sterioid when needed, and all the other 'normal' cocktail. I have experimented with taking both injections on the same day (i did NOT find taht worked well for me!!), the benlysta on Friday and the MTX on Saturday-and have found that my 'best' is MTX on Friday night, Benylsta on Saturday.
The injection is very uncomfortable to me. I numb my thigh for a good half an hour with an ice pack and am very careful to bring the injection to room temp before doing it- it burns pretty intensely if I don't do these things. The next day is my 'day', I get the nausea from the MTX and headache from the Benylsta, fatigue from both-but Monday? It is like I'm a new woman. I truly believe it is helping and we may be able to cut back on the MTX a bit soon. It is made to work with other traditional Lupus treatments, so I don't think I'll ever be totally 'off' the MTX, until I'm in remission- a dream that we all hold dear!!
Over all? I find it to be totally worth the migraine and fatigue, and injection site discomfort. I DO take phenergen most of the week to deal with the nausea from the MTX.

I'll be able to report back as to how much it is helping soon, I think. The specialty pharmacy has messed up my rx and did not ship the injections to me for this week and next- I'm hoping to have them before Christmas.
I hope that it helps you as much as it has helped me- I love doing the at home injection because my Rheumy said that many of her pts reported that the infusion doesn't last the entire month and the last week is miserable. I do premed with benedryl, phenergen, and lots and lots and lots of water, per her instructions.
Gentle hugs and lots of improvement to you!!

Almost four months with benlysta having dosis every 15 days. It is a strong med it make feel really really tired for the next 2-3 days i sleep like 12 hours ,also during infusion i always fall sleep. The effects of the medicine take time to happen, only until today i can see some improvement with the medicine but is worth it. Also the first times i took it was strong for my body and make me have more join pain.