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Real members of MyLupusTeam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.

Is everyone aware that the recommended maximum daily dose of HCQ is 5 mg/kg of your body weight?

A MyLupusTeam Member asked a question 💭
Pittsboro, NC

This dosing markedly reduces the risk of retinal/eye toxicity and probably other side effects. You can calculate this by taking your body weight in pounds, dividing it by 2.2, and multiplying by five. This number is the maximum daily dose in mg of HCQ that ophthalmologists recommend for eye safety.

Please discuss this with your rheumatologist if you're on a larger dose, and don't change it on your own. I've noticed some of us are taking too much and wanted to remind everyone.

October 18, 2024
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Answer Summary

Members enthusiastically thanked someone for sharing a helpful formula to calculate the maximum safe daily dose of hydroxychloroquine based on... Read more

Members enthusiastically thanked someone for sharing a helpful formula to calculate the maximum safe daily dose of hydroxychloroquine based on body weight, with most finding reassurance that their current prescriptions fell within the recommended range. Several members shared their personal dosages and calculated results, with many planning to discuss the information with their rheumatologists at upcoming appointments, while a few noted they had already discontinued the medication due to retinal damage. A recurring theme was the critical importance of regular eye exams with an ophthalmologist who specializes in the macula, as members recognized that everyone responds differently to the medication and vigilant monitoring is essential for long-term safety.

MyLupusTeam

It's important to be aware of the recommended maximum daily dose of hydroxychloroquine (HCQ) to minimize the risk of retinal and other side effects. Here are some key points:

- Recommended Dose: The maximum daily dose of HCQ is 5 mg/kg of body weight
- Calculation: To calculate this
1. Take your body weight in pounds.
Show Full Answer

It's important to be aware of the recommended maximum daily dose of hydroxychloroquine (HCQ) to minimize the risk of retinal and other side effects. Here are some key points:

- Recommended Dose: The maximum daily dose of HCQ is 5 mg/kg of body weight.
- Calculation: To calculate this:
1. Take your body weight in pounds.
2. Divide it by 2.2 to convert to kilograms.
3. Multiply by 5 to get the maximum daily dose in mg.

For example, if you weigh 150 pounds:
- 150 / 2.2 = 68.18 kg
- 68.18 * 5 = 340.9 mg

So, the maximum recommended dose would be approximately 341 mg per day.

- Consult Your Doctor: Always discuss any concerns about your dosage with your rheumatologist. Do not adjust your dose on your own.

This information is crucial for maintaining eye health and preventing potential side effects.

October 18, 2024
A MyLupusTeam Member

@Kham2--I'd discuss it with your rheumatologist and ophthalmologist, Kham.

October 20, 2024
A MyLupusTeam Member

I used to go into flare-ups if I tried to go below 5 mgs of prednisone. For the last couple of years I did well on 2.5 mg. With Benlysta I was able to stop taking it completely. Everyone has a different experience with Prednisone. I hope that you will feel better soon.

October 20, 2024 (edited)
A MyLupusTeam Member

@A MyLupusTeam Member I did not know this. I take 200mg BID, but according to your info I should be 300 mg total daily. I see my dr next Monday.

October 21, 2024
A MyLupusTeam Member

@JoyFargo--You may want to talk with your doctor about whether you need a slower taper of the dose. If you've been on it a long time, your body needs more time to adjust.

October 21, 2024

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