My C3 and C4 complement levels have been low x2 now. The first time they were low, my rheumatologist tried to say it was because of a lab error. I questioned it stating I was sick and have other symptoms. They had me repeat them at the hospital thinking they would be normal as they were in the past. Well what do you know, they were low again! I I’m feeling frustrated with my rheum’s comments and mostly venting (I also have had an elevated ds dna for nearly 3 yrs and protein in the urine). Anyone… read more
Low C3 and C4 complement levels, along with elevated anti-dsDNA antibodies and protein in the urine, are significant markers often associated with lupus activity, particularly lupus nephritis. It's understandable to feel frustrated if your concerns aren't being fully acknowledged. These findings suggest active disease or Show Full Answer
I would ask them to run the protein-creatinine ratio every 3 months, personally, as the urine dip test is far less accurate.
30-50 protein in urine on last few urinalysis. Better than before. They didn’t run a protein creatinine ratio this time. Blood renal function has been stable
I agree! How are your urinalysis and urine protein/creatinine doing? Low complements can signal a kidney or other organ flare, especially when you're feeling worse.
Thank you! I don’t believe the lab made an error twice, especially when I’ve having worsening symptoms as well.