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Real members of MyLupusTeam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.
A MyLupusTeam Member asked a question 💭
Oswego, NY

I have mixed connective tissue disease which includes lupus

June 25, 2025
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A MyLupusTeam Member

The AI answer is true, Anna, but over the decades, there have been times when my inflammatory markers and complement levels are normal, but joint pain and fatigue persist. Conversely, there have been times when my inflammation levels were high, but my symptoms were very mild.

With severe flares involving organs, the markers are definitely elevated. The markers and general systemic symptoms don't necessarily correlate.

June 25, 2025
MyLupusTeam

While blood tests can't directly measure pain levels, they can detect signs of inflammation and disease activity that may be causing your pain. Your rheumatologist will typically order several types of blood tests including:

• Complete blood count (CBC)
• Complement levels
• Antibody tests
• Autoimmune panel Your doctor will Show Full Answer

While blood tests can't directly measure pain levels, they can detect signs of inflammation and disease activity that may be causing your pain. Your rheumatologist will typically order several types of blood tests including:

• Complete blood count (CBC)
• Complement levels
• Antibody tests
• Autoimmune panel Your doctor will use these test results along with:

• Your reported symptoms
• Physical examination findings
• Imaging tests when needed
• Neurological exam results if you have specific symptoms

This comprehensive approach helps your rheumatologist understand disease activity and develop the most effective treatment plan for managing your symptoms, including pain.

June 25, 2025

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