Yes, azathioprine (Imuran) is considered safe to use during pregnancy. It's included on the list of lupus medications that are generally considered pregnancy-safe, along with:
• Hydroxychloroquine
• Chloroquine
• Low-dose corticosteroids (like prednisone)
• Sulfasalazine
• Tacrolimus
• Cyclosporine However, there are some Show Full Answer
Yes, azathioprine (Imuran) is considered safe to use during pregnancy. It's included on the list of lupus medications that are generally considered pregnancy-safe, along with:
• Hydroxychloroquine
• Chloroquine
• Low-dose corticosteroids (like prednisone)
• Sulfasalazine
• Tacrolimus
• Cyclosporine However, there are some lupus medications that need to be stopped before pregnancy, including:
• Cyclophosphamide
• Leflunomide
• Methotrexate
• Mycophenolate and mycophenolic acid
Most medications on this "stop list" should be discontinued at least three months before trying to conceive. Some require a specific process to clear them from your body. Never stop any medication without consulting your healthcare team first, as stopping abruptly could trigger a flare. For pain management during pregnancy, acetaminophen is generally considered safe. NSAIDs can be taken until the third trimester, at which point they must be stopped for the safety of the baby's developing circulation. Blood thinners like heparin and aspirin may also be safely used during pregnancy when needed.
August 21, 2025
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