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Real members of MyLupusTeam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.

can a ANA test be a false positive

A MyLupusTeam Member asked a question 💭
September 29, 2025
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What Is Borderline Lupus? Diagnosis and Progression Read Article...
A MyLupusTeam Member

@PhyllisKoren--Generally, flu and Covid vaccines are recommended for us in September to October yearly. These are NOT live vaccines and are safe, even for the immunocompromised.

For those of us who are immunocompromised (on any med other than HCQ), a spring COVID booster has also been recommended over the past few years. Live vaccines are generally not recommended for us, but if you're unsure about your specific needs, it's best to consult with your doctor.

October 6, 2025
A MyLupusTeam Member

Is it safe to get vaccines with Lupus and if so, when is a good time to say get a flu shot? I know not when I am having a bad flare and on methylprenisone, but when?

October 5, 2025
A MyLupusTeam Member

Yes, older people, especially, can have a low positive level, as autoantibodies tend to occur with age without causing disease. ANA by itself does NOT diagnose lupus, either, Lacee, as I'm sure you know. A whole group of symptoms, signs, and lab findings is required.

October 2, 2025
MyLupusTeam

Yes, ANA tests can sometimes give false positive results. While about 98% of people with lupus test positive for ANA, approximately 15% of healthy people may also have a positive ANA test without having lupus. This is why an ANA test alone isn't enough for a diagnosis.

Here's what you should know about ANA test accuracy
• Show Full Answer

Yes, ANA tests can sometimes give false positive results. While about 98% of people with lupus test positive for ANA, approximately 15% of healthy people may also have a positive ANA test without having lupus. This is why an ANA test alone isn't enough for a diagnosis.

Here's what you should know about ANA test accuracy:
• ANA test results can change over time
• Test results need to be interpreted by your healthcare provider who knows your medical history
• A positive result is just one piece of the diagnostic puzzle To ensure an accurate lupus diagnosis, doctors typically order additional tests after a positive ANA, including:
• Additional autoantibody tests (like anti-dsDNA)
• Complete blood count
• Complement level tests
• Urinalysis
• Inflammation markers

These additional tests, combined with your symptoms and medical history, help create a more complete diagnostic picture.

September 29, 2025

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Can a positive ANA test be positive and on a new test be negative

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St Petersburg, FL
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