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Real members of MyLupusTeam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.
A MyLupusTeam Member asked a question 💭
Ventura, CA
October 22, 2025
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MyLupusTeam

Yes, lupus can cause both constipation and diarrhea. Between 40-60% of people with lupus experience digestive symptoms. These bowel changes occur because lupus can cause inflammation in various parts of your digestive system, including your intestines, nervous system, and other abdominal organs. Several factors can Show Full Answer

Yes, lupus can cause both constipation and diarrhea. Between 40-60% of people with lupus experience digestive symptoms. These bowel changes occur because lupus can cause inflammation in various parts of your digestive system, including your intestines, nervous system, and other abdominal organs. Several factors can contribute to these digestive issues:

• Direct inflammation from lupus affecting the digestive tract
• Development of conditions like GERD or IBS
• Intestinal pseudo-obstruction (where the body acts as if there's a bowel blockage)
• Side effects from lupus medications
• Nervous system changes that affect digestive regularity

If you're experiencing persistent digestive issues, it's important to discuss them with your healthcare provider to determine the specific cause and appropriate treatment.

October 22, 2025
A MyLupusTeam Member

I’m on Slirizi now for my colon.

October 22, 2025

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