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Real members of MyLupusTeam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.
December 21, 2025
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Has anyone been prescribed dapagliflozin for lupus nephritis, and did you experience weight loss?

The search results don't specifically mention dapagliflozin being prescribed for lupus nephritis. However, lupus nephritis is commonly treated with medications like ACE inhibitors, angiotensin-receptor blockers, and diuretics to Show Full Answer

Has anyone been prescribed dapagliflozin for lupus nephritis, and did you experience weight loss?

The search results don't specifically mention dapagliflozin being prescribed for lupus nephritis. However, lupus nephritis is commonly treated with medications like ACE inhibitors, angiotensin-receptor blockers, and diuretics to help control blood pressure and reduce protein in the urine.

Weight changes with lupus nephritis can happen for several reasons:

- Fluid retention from kidney damage can cause weight gain and swelling
- Diuretics used to treat lupus nephritis help remove excess fluid, which may lead to weight loss
- Some lupus medications, particularly corticosteroids, are associated with weight gain

A MyLupusTeam member shared: "Was just diagnosed a month ago with 4&5 nephritis lupus. Having major issues with feet swelling. Any suggestions to help with the swelling or ideas how long it takes to get rid of the fluid build up?"

If you've been prescribed dapagliflozin, it's important to discuss any weight changes with your healthcare team, as they can help determine whether it's related to the medication, fluid loss, or other factors related to your lupus treatment.

December 21, 2025

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