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Have been diagnosed for a year, multiple symptoms and many reactions to medications so now on prednisone, nortriptoline, azathyioprine, feet are getting so bad it’s tricky to walk. Pad my shoes with many soft sole options that helps as much as possible. Blood tests are fine.

December 23, 2025
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What can help with extremely painful, red, and hot feet from lupus?

The red, hot, and painful soles you're experiencing could be related to several lupus-related conditions. Arthritis is the most common cause of foot pain in lupus, affecting about 95 percent of people at some point. Even without visible swelling, joint Show Full Answer

What can help with extremely painful, red, and hot feet from lupus?

The red, hot, and painful soles you're experiencing could be related to several lupus-related conditions. Arthritis is the most common cause of foot pain in lupus, affecting about 95 percent of people at some point. Even without visible swelling, joint inflammation can cause significant pain and burning sensations.

Another possibility is chilblain lupus, a rare skin form of lupus that causes painful sores or patches on the feet, including the soles and heels. These can appear red or purple and are often triggered or worsened by cold and moisture.

Some MyLupusTeam members describe similar experiences:
- "My feet feel like I'm walking on glass whenever I walk"
- "The burning and pain I experience is horrible"
- "Does anyone feel as though you're walking on rocks?" Here are some helpful approaches to consider:

Immediate relief options:
- Continue padding your shoes with soft insoles (you're already doing this well!)
- Keep your feet warm with comfortable socks, as cold can worsen symptoms
- Limit walking when possible to reduce pain triggers

Medical treatments to discuss with your doctor:
- Anti-inflammatory medicines like NSAIDs may help with joint pain
- Antimalarial medications are sometimes used for lupus arthritis
- Blood pressure medicines can improve circulation if that's contributing
- A referral to a podiatrist (foot specialist) for targeted treatments

Since you've had reactions to medications before, it's especially important to talk with your healthcare provider about these symptoms. They can determine the underlying cause and adjust your treatment plan safely.

December 23, 2025

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