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A MyLupusTeam Member asked a question 💭
Otsego, MI
March 24
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Are you considering Zepbound for sleep apnea and weight loss with lupus?

Zepbound (tirzepatide) is a dual-incretin therapy that was FDA-approved in 2023 for chronic weight management in adults with obesity or overweight with at least one weight-related condition. It works by mimicking hormones that help regulate appetite and Show Full Answer

Are you considering Zepbound for sleep apnea and weight loss with lupus?

Zepbound (tirzepatide) is a dual-incretin therapy that was FDA-approved in 2023 for chronic weight management in adults with obesity or overweight with at least one weight-related condition. It works by mimicking hormones that help regulate appetite and blood sugar.

Research on these medications specifically for people with lupus is still limited. One small study found that GLP-1 medications (a similar class of drugs) helped reduce BMI in people with lupus without triggering flares. However, there are rare case reports of drug-induced lupus associated with similar medications, though these reports are uncommon and don't prove causation.

On a positive note, GLP-1 receptor agonists have shown additional cardiovascular and kidney protective benefits in patients with lupus nephritis, though more research is needed in this area.

It's crucial to consult your healthcare team before starting Zepbound or any weight loss medication. They can evaluate your individual circumstances, including your lupus activity, other medications, and potential risks to ensure it's safe for you. Over-the-counter weight loss options can interfere with lupus treatment, so always discuss these decisions with your care team first.

March 24

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