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A MyLupusTeam Member asked a question 💭
Aliso Viejo, CA
April 29
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CRP (C-reactive protein) is a protein made by the liver that rises in response to inflammation. A CRP level less than 1 mg/L is generally considered normal or low, suggesting there is little to no significant inflammation detected in the body at that time.

For someone with lupus, this can actually be a bit of a mixed signal Show Full Answer

CRP (C-reactive protein) is a protein made by the liver that rises in response to inflammation. A CRP level less than 1 mg/L is generally considered normal or low, suggesting there is little to no significant inflammation detected in the body at that time.

For someone with lupus, this can actually be a bit of a mixed signal. Lupus is known for sometimes showing low or normal CRP levels even during a flare, which is one of the quirks that makes it different from other inflammatory conditions. So a low CRP doesn't always mean everything is perfectly calm.

Here's what a low CRP result might mean in the context of lupus:

- Disease activity may be low — it could indicate your lupus is relatively well-controlled at that moment
- It may not tell the whole story — lupus flares don't always raise CRP significantly, so other markers like ESR (erythrocyte sedimentation rate) or anti-dsDNA antibodies are also used to monitor disease activity
- It's one piece of the puzzle — doctors typically look at a full panel of blood tests together, not just CRP alone

It's always worth discussing your specific results with your doctor or rheumatologist, as they'll interpret your CRP alongside your other test results and how you're feeling overall.

April 29

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