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I had diarrhea nearly every day for a solid 4 months. Started meds 6 weeks ago. No diarrhea for 5 days now. Could this be due the Plaquenil

A MyLupusTeam Member asked a question 💭
Hannibal, MO

I had diarrhea as part of the symptoms for 4 mo before starting meds. Been on meds for a month now and it's finally stopped. Could it be related to meds

May 3
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A MyLupusTeam Member

Yes, it's possible the PLQ is helping your diarrhea, Teresa. You may want to ask your doctor about whether they want to test you for celiac disease, as it's also autoimmune, and we are more prone to other autoimmune conditions.

May 3
MyLupusTeam

Yes, diarrhea is a known side effect of hydroxychloroquine (Plaquenil). It's one of the more common gastrointestinal side effects people experience when starting the medication.

The good news is that these digestive side effects — including diarrhea, nausea, and stomach cramps — typically improve after a few days as the body Show Full Answer

Yes, diarrhea is a known side effect of hydroxychloroquine (Plaquenil). It's one of the more common gastrointestinal side effects people experience when starting the medication.

The good news is that these digestive side effects — including diarrhea, nausea, and stomach cramps — typically improve after a few days as the body adjusts to the medication. Here are a few tips to help manage stomach-related side effects:

- Take hydroxychloroquine with food to help reduce stomach upset
- Drink plenty of water and avoid skipping meals when taking the medication
- Take it with milk as an alternative to help ease nausea

If diarrhea or other gastrointestinal symptoms persist or become severe, it's worth reaching out to a doctor. Prolonged diarrhea can sometimes lead to appetite changes or weight loss, which are worth monitoring.

May 3

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