Cutaneous lupus erythematosus (CLE) primarily affects the skin, and the available research on lupus-related blood abnormalities focuses more on systemic lupus erythematosus (SLE). Low serum total protein and globulin levels aren't well-documented as direct effects of CLE specifically.
However, in SLE, the immune system can Show Full Answer
Cutaneous lupus erythematosus (CLE) primarily affects the skin, and the available research on lupus-related blood abnormalities focuses more on systemic lupus erythematosus (SLE). Low serum total protein and globulin levels aren't well-documented as direct effects of CLE specifically.
However, in SLE, the immune system can cause a range of blood abnormalities. These include:
- Anemia (low red blood cells) — affects about 50% of people with SLE
- Leukopenia (low white blood cells) — affects 50%–60% of people with SLE
- Thrombocytopenia (low platelets) — affects 20%–40% of people with SLE
- Lymphopenia (low lymphocytes) — affects 75%–90% of people with SLE
Protein levels can be indirectly affected by lupus-related kidney involvement (lupus nephritis), where protein can be lost through urine, potentially lowering serum protein levels.
It's really worth discussing any abnormal lab results with a rheumatologist or hematologist, as they can best interpret what's driving those specific changes in the context of a lupus diagnosis.
May 21
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