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I am anxious about starting on 7mg soon for Lupus SLE, RA and Sjoghrens.

May 23
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A MyLupusTeam Member

Thank you.

May 23
MyLupusTeam

Starting a new medication can feel nerve-wracking, and those feelings are completely valid. The good news is that at lower doses like 7mg, the risk of side effects — including hair loss — is generally lower compared to higher doses.

Hair loss is listed as a possible side effect of methotrexate, but it's not guaranteed, and Show Full Answer

Starting a new medication can feel nerve-wracking, and those feelings are completely valid. The good news is that at lower doses like 7mg, the risk of side effects — including hair loss — is generally lower compared to higher doses.

Hair loss is listed as a possible side effect of methotrexate, but it's not guaranteed, and many people tolerate lower doses well. Taking folic acid daily (as most doctors recommend alongside methotrexate) can help reduce some side effects, particularly mouth sores and other issues related to how methotrexate affects folate in your body. Other side effects to be aware of at any dose can include:

- Nausea, vomiting, or upset stomach
- Diarrhea or loss of appetite
- Mouth sores
- Fatigue and weakness
- Headache
- Dizziness
- Skin sensitivity to sunlight

These may be more noticeable at higher doses, so starting at 7mg is often a cautious and sensible approach.

It's always worth flagging any new symptoms to your rheumatologist promptly, especially things like black stool or shortness of breath, which would need attention right away.

May 23

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