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Real members of MyLupusTeam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.
June 4
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A MyLupusTeam Member

That's not a very high antibody titer (or level), Frankie, which is a good thing.

June 4
MyLupusTeam

A positive ANA test using a HEp-2 substrate means the lab used human cells to detect antinuclear antibodies in the blood — it's actually the most common and sensitive method used for this test. Here's a breakdown of the results:

- Positive result — Antinuclear antibodies were found in the blood
- Titer of 1:320 — This is Show Full Answer

A positive ANA test using a HEp-2 substrate means the lab used human cells to detect antinuclear antibodies in the blood — it's actually the most common and sensitive method used for this test. Here's a breakdown of the results:

- Positive result — Antinuclear antibodies were found in the blood
- Titer of 1:320 — This is considered a high titer, meaning a significant level of antibodies was detected. A result of 1:80 or above is generally considered positive, so 1:320 is notably elevated
- Homogeneous pattern — This means the antibodies are spread evenly across the cell nucleus under the microscope, and is one of the patterns most commonly associated with lupus It's important to know that a positive ANA alone doesn't confirm a lupus diagnosis. Around 15% of healthy people can also test positive. Doctors use the ANA result alongside symptoms and additional tests — like anti-double-stranded DNA — to build the full picture.

Sharing these specific results with a rheumatologist is really the best next step, as they can interpret them alongside personal health history and symptoms.

June 4
A MyLupusTeam Member

Very few people with PMR get TA--I've read about 10-20%. Just watch for headaches in the temple or vision changes.

June 6
A MyLupusTeam Member

Good. That was the last bloodwork result I got in. One question. If this is actually PMR how concerning is Giant Cell Arteritis?

June 4

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Naperville, IL