Yes, lupus and menopause can be a tough combination. Lupus can actually cause early menopause, partly due to the condition itself and certain medications like corticosteroids and cyclophosphamide, which can affect how the ovaries function.
Hormonal shifts during menopause can also trigger lupus flares, making symptoms feel Show Full Answer
Yes, lupus and menopause can be a tough combination. Lupus can actually cause early menopause, partly due to the condition itself and certain medications like corticosteroids and cyclophosphamide, which can affect how the ovaries function.
Hormonal shifts during menopause can also trigger lupus flares, making symptoms feel more intense during this time. As one MyLupusTeam member put it, "Hormone shifts seem to trigger flares." Some common menopause symptoms that can overlap with or be worsened by lupus include:
- Hot flashes and night sweats — lupus can affect the autonomic nervous system, which regulates body temperature
- Mood swings and trouble sleeping
- Irregular periods leading up to menopause
- Increased lupus flares due to fluctuating estrogen levels
Hormone replacement therapy (HRT) is sometimes used to manage menopause symptoms, but it's not suitable for everyone with lupus — it can trigger flares or increase the risk of blood clots. It's worth having an open conversation with a doctor about what options are safest given a specific treatment plan.
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