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Real members of MyLupusTeam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.
August 24
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A MyLupusTeam Member

Some of the recent COVID variants cause a razor-blade sore throat, Heather, so please test for that and see your doctor. It's possible it's lupus-related, but I would rule out an infection first.

August 25
MyLupusTeam

That combination of razor-blade throat pain and mouth sores sounds really miserable — and you're definitely not alone. Many MyLupusTeam members describe similar experiences, with some saying throat pain during swallowing feels completely different from a typical illness-related sore throat.

With lupus, there are a few Show Full Answer

That combination of razor-blade throat pain and mouth sores sounds really miserable — and you're definitely not alone. Many MyLupusTeam members describe similar experiences, with some saying throat pain during swallowing feels completely different from a typical illness-related sore throat.

With lupus, there are a few reasons this can happen:

- Mouth and throat ulcers — About 25% of people with lupus develop sores in or around the mouth and throat, which can make swallowing extremely painful
- Lupus flares — Flares can trigger these sores directly
- Medication side effects — Some lupus medications, like methotrexate or corticosteroids, can cause or worsen mouth sores
- Infections — Because many lupus medications suppress the immune system, infections become more likely and can cause severe throat pain
- Swollen lymph nodes — These are common during flares and can add to throat discomfort It's really important to contact your doctor or rheumatologist soon, especially to rule out an infection that may need treatment. Don't try to self-diagnose or treat with over-the-counter medications without checking first, as some can interact with lupus medications like methotrexate.

August 24

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