Yes, lupus can cause hives (also called urticaria). About 10% of people with lupus develop them. While hives are often linked to allergic reactions, hives that last longer than 24 hours are usually caused by lupus itself. Lupus-related hives can appear as itchy bumps or raised patches of skin, either individually or in Show Full Answer
Yes, lupus can cause hives (also called urticaria). About 10% of people with lupus develop them. While hives are often linked to allergic reactions, hives that last longer than 24 hours are usually caused by lupus itself. Lupus-related hives can appear as itchy bumps or raised patches of skin, either individually or in groups. They can be quite uncomfortable and persistent.
A few things worth knowing:
- Hives lasting more than 24 hours are more likely lupus-related than allergy-related
- They can also be triggered by a medication reaction or lupus-related vasculitis
- A dermatologist can help rule out other causes and find the right treatment
It's important to let your doctor know about any new or worsening skin symptoms, especially if hives persist, as some related conditions like cutaneous vasculitis can cause serious complications if left untreated. Some people find relief using antihistamines like Benadryl (diphenhydramine) for the itchiness and discomfort. One MyLupusTeam member shared, "When Benadryl is taken, the buzzing and itchiness stop." However, antihistamines treat the hives themselves, not the underlying lupus inflammation, so always follow your doctor's guidance on treatment.
October 11
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