Antidepressants for pain?

Antidepressants for pain?

Anyone know of any good antidepressants that can also help with joint pain, neuropathy, and hot "flashes"/burning sensations? The only two that come into mind that I can think of are Cymbalta and Effexor. I'm thinking of asking my doctor about Cymbalta, but I'd like to know if anyone has either tried that one or know of any others. And what side effects, if any, do you experience (weight changes, fatigue, dizziness/confusion, hair loss, etc)?
Also, which ones(s) is best for extreme panic… read more

A MyLupusTeam Member said:

Hi @A MyLupusTeam Member! I’m an inpatient psychiatric nurse so know about these meds. I think Cymbalta is your best bet for a trial of a medication that can touch a lot of your symptoms mentioned. Depression/anxiety/chronic pain/neuropathy. Gabapentin hits anxiety and pain—especially neuropathic pain. Lyrica (pregabalin) is another good one—often used for fibromyalgia pain, neuropathic pain, etc. it can also help w/ anxiety like gabapentin. Lyrica is a bit pricey, though. Everyone’s bodies process meds differently so it’s hard to say what will help you the most, but I think any of these meds are worth trying—that said, I am not a doctor, just passing along some information that I hope will help!☺️

posted 4 months ago
A MyLupusTeam Member said:

With all due respect, I did not command an all out assault on Amytriptyline, I merely stated a one sentence experience based on me and me only.

For the record, good sleep for me is over 4 hours, I did not sleep all the time nor did my general activity become reduced, I became ravenously hungry. After a 120 lb weight loss with extreme every day nausea for over 4 years now I can safely deduce that this medication activated my hunger to the extreme as it abruptly ended with the use of said medication.

***For anyone reading any of my posts, please understand that I am not a Doctor or medical provider, I am simply here for support and answers like everyone else and only share MY personal experience which I will be more careful with in the future. Also keep in mind we are all individuals having individual results with any medication.

Have a great day!

edited, originally posted 3 months ago
A MyLupusTeam Member said:

I take cymbalta the side affects for me was just feeling loopy, sleepy all the time and i had a upset stomach, vomitting, and nausea but that only lasts for about a week or two. My mood was a lot better though when it comes to the depression side it kind of numbed me

posted 4 months ago
A MyLupusTeam Member said:

I’ve been on Prednisone off and on for 3 years. Currently on a daily maintenance dose for 3 months, no weight gain, no puffiness, no swelling and no increase in appetite. Opposite of most taking steroids. I’ve been on Plaquenil for 2 years, no weight gain.

My illnesses started in my 20’s, I’m approaching 49 in a few months, I’ve taken many medications over these years, not sure about “misunderstanding Amytriptyline “ however, I do understand that we as humans are not monolithic and have many reactions to different pharmaceuticals.

My doctor confirmed that Amytriptyline can cause some people to gain weight. I was always a large girl, 3 years ago after a spinal surgery all of my autoimmune issues surfaced with a vengeance hence my 120lb weight loss, no appetite and raging nausea, that’s when my medications were started so my nausea was in existence prior to being on any medication, I was very much a natural remedy person very anti pharmaceutical after years (in my 20s and 30s) of multiple pills that did nothing for me. The natural route was no longer a viable option alone.

I became extremely in tuned to my body during this time

2 things have stimulated my appetite in this 3 years, medical cannabis (RSO) and Amytriptyline.

posted 3 months ago
A MyLupusTeam Member said:

I slept great on Amytriptyline and I put on a FAST 15lbs. Stopped taking it and dropped the weight right away.🤷‍♀️

posted 3 months ago
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