My only abnormal labs were ANA and RF. All the other ones have been negative. While labs are important, they are (or should be) a small part of diagnosis. I had two previous physicians that relied too heavily on labs and wouldn't give me a diagnosis for almost 2 years. Third doctor was a Lupus specialist and told me the first appointment it was definitely Lupus based on my symptoms and the positive ANA. It was very validating and I'm finally getting the care I need. I hope you get answers soon.

The dermatologist numbed a small spot along my chin line and just took a small piece out. Only took about 2 min in office.

Redeyedann, what is a punch biopsy?

Your ANA can change based on whether it is active or not. Mine does. I was diagnosed by my dermatologist doing a punch biopsy after her taking 1 look at me. This is after 8 yrs of symptoms.

As we all know there is no clearcut test for lupus but the Dr tested my AntiDNA, Rheumatoid factor, anti nuclear antibodies and c reactive protein along with the regular bloodwork. And done biopies