Yes I’ve been on 400 mg for 20 years still go in every 6 months for eye check up

Hi @A MyLupusTeam Member.

This article says…

The main long-term side effects of Plaquenil are eye-related. Plaquenil can damage your retina, which may lead to permanent loss of vision.

Side Effects of Plaquenil: What You Need to Know
https://www.healthline.com/health/drugs/plaquen....

In rare cases, hydroxychloroquine can cause visual changes or loss of vision. Such problems are more likely to occur in individuals taking high doses for many years, in individuals 60 years or older, those with significant kidney or liver disease, and those with underlying retinal disease. At the recommended dose, the development of visual problems due to the medication is rare. It is recommended that you have an eye exam within the first year of use, then repeat every 1 to 5 years based on current guidelines.
Additional rare reports of changes in the heart rhythm have been reported with the use of hydroxychloroquine, particularly in combination with other medications.
https://rheumatology.org/patients/hydroxychloro...

7 Hydroxychloroquine Side Effects You Should Know About
https://www.goodrx.com/hydroxychloroquine/plaqu...

Plaquenil side effects and how to avoid them (See Eye Problems)
https://www.singlecare.com/blog/plaquenil-side-...

Plaquenil Alternatives Compared
https://www.drugs.com/compare/plaquenil

Natural Alternatives to Hydroxychloroquine
https://www.mynaturaltreatment.com/natural-alte...

Ok , I hope this helps you make the right decision for you. God bless and get well soon.

Mentioned Users

A MyLupus...

Yes, retinal toxicity is a possible side effect. Getting eyes tested regularly, and taking the lowest dose that's effective is advisable.

Yes

yes it is advised as a precaution