Common thought is that you can have a genetic predisposition to Lupus. It does run in families, though it's far from universal. At this time, no single gene or genetic grouping is linked to Lupus.

Combination of genes and environmental triggers.

There is a genetic predisposition, and it's thought that an infection may often be the trigger, as our immune systems are activated. This DOES NOT mean that your children will get it, but they are at higher risk.

I developed Lupus and RA and no one in my family has it. 😔😔

Yes, It is I. the Blood! My oncologist and hemotologist made clear that mines began from birth and probably from my paternal grandmother who suffered with severe rheumatoid arthritis arms a very young age! I was very sickly at birth throughout my childhood adolescence and they diagnosed me and told my parents I wa Anmic ( partly right) post menopause my hemotologist diagnosed me with autoimmune hemolytic anemia which going so long undiagnosed I developed best Cancer Stage 2/borderline three that was very aggressive! I'm 10 years in remission although Sjrogens Syndrome/Lupus came in 2017 after major problems with my whole/ entire body that they attributed to side effects of the amount of chemo and radiation required
to survive. However with a 2nd opinion they rejected the chemo theory and by the Grace of I was saved, clearly diagnosed regarding the breaking down of my body inside and healed of the breast cancer. He guided the wisdom and the hands of the doctors to begin this Sjrogens/ Lupus Journey as it continues...Psalm 23.....It was in my blood! Pray my St
Rather as I continue to pray for all sufferers🙏🏿🙏🏿The struggle is real because most people see me but don't see me because I look fine out side!!

I thought it was Evangaline. Thank you for replying