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Real members of MyLupusTeam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.
July 7, 2025
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A MyLupusTeam Member

Thank you, yes he did prescribe the Folic acid as well and he did say we can switch it to subq injections if necessary. But i do appreciate this. I’m a nurse and I am well aware that all medications come with side effects but starting new medications always give me anxiety.

July 7, 2025
A MyLupusTeam Member

I've been on it for years. I started with the pills and a couple years later, switched to injections because I started having stomach upset. I don't have any side effects with the injections. Make sure to take your folic acid, especially the day off and day after for both forms but especially the pills (I take 2mg daily and 5mg the day of and day after). If you have nausea, they can up the dosage of the folic acid. I'm on a cocktail now of immunosuppressants but I can sure tell when im off the MTX(methotrexate). The pills made me sleepy the next day. I really hope it helps.

July 7, 2025
MyLupusTeam

It's completely normal to feel anxious about starting a new medication. Methotrexate is typically taken once a week and works by calming your overactive immune system to help decrease lupus symptoms.

Common side effects may include
- Nausea and upset stomach
- Fatigue and weakness
- Loss of appetite
- Mouth sores
- Headache Show Full Answer

It's completely normal to feel anxious about starting a new medication. Methotrexate is typically taken once a week and works by calming your overactive immune system to help decrease lupus symptoms.

Common side effects may include:
- Nausea and upset stomach
- Fatigue and weakness
- Loss of appetite
- Mouth sores
- Headache
- Hair loss Here are some tips to help manage your treatment:

1. Take your medication exactly as prescribed
2. Don't stop taking methotrexate without talking to your rheumatologist first
3. Report any concerning side effects to your doctor right away
4. Be especially mindful if you experience black stool or severe stomach pain, as these require immediate medical attention

Many MyLupusTeam members report positive experiences with methotrexate, noting improvements in joint pain and other lupus symptoms. Remember that your doctor prescribed this medication because they believe its benefits outweigh potential risks for your specific situation.

July 7, 2025
A MyLupusTeam Member

I tried it before, but made my hair fall out! I pray it works for you!
I’m now getting infusions.

July 8, 2025

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