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Real members of MyLupusTeam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.
September 22, 2025
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A MyLupusTeam Member

Sometimes it takes a while for it to show up sometimes. My dr at first went by my family history I don’t know if lupus is passed through families but RA is and that’s where I get it from I lovingly call it the Hunsaker ( my last name) curse lol my family doesn’t see it as funny oh well lol

September 24, 2025
MyLupusTeam

It's possible to have lupus even with negative ANA test results. This is known as ANA-negative lupus, which can be diagnosed particularly if there is evidence of lupus nephritis from a kidney biopsy. Your symptoms should still be taken seriously, even if your blood work has changed.

When test results change but symptoms Show Full Answer

It's possible to have lupus even with negative ANA test results. This is known as ANA-negative lupus, which can be diagnosed particularly if there is evidence of lupus nephritis from a kidney biopsy. Your symptoms should still be taken seriously, even if your blood work has changed.

When test results change but symptoms persist, your rheumatologist may need to order additional tests to better understand what's causing your symptoms. These might include:

• Complete blood count (CBC)
• Complete metabolic panel (CMP)
• Complement levels (C3 and C4)
• Erythrocyte sedimentation rate (ESR)
• C-reactive protein (CRP)
• Urinalysis Stay in open communication with your healthcare team about your ongoing symptoms and test results. Even if you don't currently meet all the standard criteria for active lupus, your treatment plan may still need to focus on managing your specific symptoms. Your doctor can help interpret your test results in the context of your overall health history and current symptoms.

September 22, 2025

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Swansea, UK