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A MyLupusTeam Member asked a question 💭
Eugene, OR
December 3, 2025
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A MyLupusTeam Member

This isn't an extremely high titer, but it is abnormal, Deana. ANA is not specific for lupus and is seen in many autoimmune diseases. Have you had a full antibody panel run by your doctor yet?

December 5, 2025
MyLupusTeam

A titer of 1:180 refers to the concentration of antinuclear antibodies (ANAs) found in your blood test. The number indicates how much your blood sample was diluted while still showing a positive result for these antibodies.

In the ANA test, your blood is diluted in steps (like (Phone number can only be seen by the question Show Full Answer

A titer of 1:180 refers to the concentration of antinuclear antibodies (ANAs) found in your blood test. The number indicates how much your blood sample was diluted while still showing a positive result for these antibodies.

In the ANA test, your blood is diluted in steps (like (Phone number can only be seen by the question and answer creators), etc.). A result of 1:180 means your sample was diluted 180 times and still tested positive for ANAs.

While many people with lupus have positive ANA tests, it's important to know that:

- Up to 15% of healthy people can test positive for ANAs
- A positive ANA alone cannot diagnose lupus
- Some medications and other conditions can cause positive results
- A small percentage of people with lupus actually test negative

Your rheumatologist will need to consider your ANA results alongside your symptoms, physical examination, and other lab tests. If your ANA is positive, they may order an ANA panel to check for specific types of autoantibodies that can help confirm a lupus diagnosis.

The ANA test is just one piece of the diagnostic puzzle, not a definitive answer on its own.

December 3, 2025

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