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Real members of MyLupusTeam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.

Anyone else experience PVC’s and/or palpitations while on hydroxychlorquine ? I’ve been taking this probably 8 months or so.

A MyLupusTeam Member asked a question 💭
Perryville, MO
December 3, 2025
 · 
Reactions
A MyLupusTeam Member

I experienced that after over 30 years on HCQ, Kathleen, and I had previously tolerated it well.

It's crucial to ensure the dose is no more than 5 mg/kg of your body weight. Larger doses are much more likely to cause retinal problems and other side effects.

December 5, 2025
MyLupusTeam

Are you experiencing PVCs (premature ventricular contractions) or heart palpitations while taking hydroxychloroquine?

Yes, heart rhythm problems can occur with hydroxychloroquine, though they're considered rare. Abnormal heart rhythm is listed as a serious side effect of this medication.

If you're noticing symptoms like
- A Show Full Answer

Are you experiencing PVCs (premature ventricular contractions) or heart palpitations while taking hydroxychloroquine?

Yes, heart rhythm problems can occur with hydroxychloroquine, though they're considered rare. Abnormal heart rhythm is listed as a serious side effect of this medication.

If you're noticing symptoms like:
- A fast or irregular heartbeat
- A "thumping" feeling in your chest
- Feeling faint or dizzy

It's important to report these to your doctor right away. Heart rhythm changes can be a sign of a serious side effect that needs medical attention.

Don't wait to address this - contact your healthcare provider as soon as possible to discuss what you're experiencing. They may want to evaluate your heart rhythm and determine if any adjustments to your treatment are needed.

December 3, 2025
A MyLupusTeam Member

I have had that and the doctor thought I was having a heart attack cuz it was around the time I found out I had Costochondritis. Then they said it was the medicine causing the heart rhythm problem

December 5, 2025

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