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Real members of MyLupusTeam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.
A MyLupusTeam Member asked a question πŸ’­
Penticton, BC
April 16
 · 
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A MyLupusTeam Member

I was taking gabapentin, but it made my symptoms worse. I take Rituxan and no major side effects. Take care and enjoy your weekend ahead.
Jerrie

April 16
A MyLupusTeam Member

I periodically get jerking from my arms or legs when I am asleep, which wakes me up. I have neuropathy and take Gabapentin at night.

April 16
MyLupusTeam

What causes those sudden jolts that make your arm or leg jump or twitch?

These involuntary muscle movements are called myoclonus or myoclonic jerks. They can happen as isolated twitches or in patterns, and they range from quick movements to more persistent contractions.

For people with lupus, several factors can trigger these Show Full Answer

What causes those sudden jolts that make your arm or leg jump or twitch?

These involuntary muscle movements are called myoclonus or myoclonic jerks. They can happen as isolated twitches or in patterns, and they range from quick movements to more persistent contractions.

For people with lupus, several factors can trigger these jolts:

Lupus-Related Causes:
* Peripheral neuropathy - Lupus can affect the nerves that send signals to and from your muscles
* Lupus flares - Some members notice twitching increases before or during flares
* Lupus myositis - Inflammation affecting the muscles themselves

Medication Side Effects:
* Gabapentin (Neurontin)
* Escitalopram (Lexapro)
* Prednisone, especially at higher doses
* Hydroxychloroquine (Plaquenil) - less common but possible

Other Common Triggers:
* Low magnesium levels
* Dehydration
* Stress or lack of sleep
* Strong emotions or anxiety
* Low blood sugar
* Too much caffeine

Many MyLupusTeam members describe these as happening more when relaxed or trying to sleep. One member shared that their body starts jerking when relaxed, which can be disruptive to rest.

If your twitching is frequent or bothersome, tracking when it happens and discussing it with your doctor can help identify the cause and find the right treatment for you.

April 16
A MyLupusTeam Member

Heather, even healthy people get myoclonus when falling asleep. Do you notice it at other times?

April 17

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