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Real members of MyLupusTeam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.
May 2
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MyLupusTeam

It looks like your question got cut off! It sounds like you're wondering about amitriptyline and how it interacts with your current antidepressant — is that right?

Here's what's helpful to know: amitriptyline is a tricyclic antidepressant. When combined with certain other antidepressants, it can affect serotonin levels in a Show Full Answer

It looks like your question got cut off! It sounds like you're wondering about amitriptyline and how it interacts with your current antidepressant — is that right?

Here's what's helpful to know: amitriptyline is a tricyclic antidepressant. When combined with certain other antidepressants, it can affect serotonin levels in a potentially dangerous way.

This can lead to something called serotonin syndrome, which in serious cases can cause:

- High fever
- Seizures
- Loss of consciousness

Your doctor is right to be cautious. The good news is there are other options worth discussing with your rheumatologist or prescribing doctor to find something that works safely alongside your current medications.

Feel free to share the rest of your question — it seems like it got cut short! 😊

May 2

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