Connect with others who understand.

  •   Learn from expert-reviewed resources
  •   Real advice from people who’ve been there
  •   People who understand what you’re going through
Sign Up Log In
All Resources Treatments A-Z Personal Assistant Help Center Crisis
Powered By
Real members of MyLupusTeam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.

Anyone have episodes of vomiting and diarrhea with severe diaphoresis usually at night?

A MyLupusTeam Member asked a question 💭
Moncks Corner, SC

Lupus Fybromyalgia Hives Angioedema Gastroporesis IBS Kidney stones Migraine Trigeminal Neuralgia Diverticulitis

May 6
 · 
Reactions
A MyLupusTeam Member

Is this a recurring problem, Cathryn? Severe onset of both is often due to food poisoning, but that shouldn't keep happening. Lupus can affect gut motility, so that or a reaction to a new medication may explain it. Have you discussed this with your rheumatologist? Do you have any chest discomfort or shortness of breath along with these episodes?

May 7 (edited)
MyLupusTeam

That sounds absolutely exhausting, and you're definitely not alone in dealing with overlapping lupus-related digestive issues at night. Many MyLupusTeam members report similar experiences with vomiting, diarrhea, and night sweats.

With lupus, several things can contribute to these episodes:

- Lupus inflammation can affect the Show Full Answer

That sounds absolutely exhausting, and you're definitely not alone in dealing with overlapping lupus-related digestive issues at night. Many MyLupusTeam members report similar experiences with vomiting, diarrhea, and night sweats.

With lupus, several things can contribute to these episodes:

- Lupus inflammation can affect the muscles of the digestive tract, disrupting normal movement of food through the gut
- IBS and diverticulitis (which you already have) can both trigger vomiting, diarrhea, cramping, and sweating episodes
- Lupus medications like NSAIDs, corticosteroids, and azathioprine can cause significant digestive side effects
- Intestinal pseudo-obstruction — where the body acts as if there's a blockage when there isn't — can cause bloating, nausea, vomiting, and diarrhea Given how many conditions you're managing simultaneously, it's really important to track these episodes carefully and report them to your rheumatologist. Note things like:

- When they happen
- How long they last
- What you ate beforehand
- Any medications taken that day
- Severity on a scale of 1–10

Severe or worsening episodes should never be ignored, as some complications like diverticulitis flares can become life-threatening. Your rheumatologist is best placed to help untangle what's driving these nighttime episodes.

May 6

Related Questions

View All
Is Lupus Joint Pain Worse at Night?
Severe Itching and Bruising With Lupus: 3 Causes
Can Hydroxychloroquine Cause Night Sweats? 7 Possible Reasons for Night Sweats