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Bayamón, PR
May 11
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MyLupusTeam

Can low CO2 levels in the blood be related to lupus?

Low CO2 levels in the blood can be connected to lupus in a few ways. CO2 is measured as part of a basic metabolic panel, and lupus can affect multiple organ systems — including the kidneys — which play a key role in regulating CO2 levels in the blood.

Here are some things Show Full Answer

Can low CO2 levels in the blood be related to lupus?

Low CO2 levels in the blood can be connected to lupus in a few ways. CO2 is measured as part of a basic metabolic panel, and lupus can affect multiple organ systems — including the kidneys — which play a key role in regulating CO2 levels in the blood.

Here are some things worth knowing:

- Kidney involvement (lupus nephritis) can disrupt the body's acid-base balance, which directly affects CO2 levels
- Lupus medications like corticosteroids can also influence electrolyte and metabolic balance
- Low CO2 can sometimes signal a condition called metabolic acidosis, where the blood becomes too acidic — this can be linked to kidney issues common in lupus

It's really important to flag low CO2 results with a doctor or rheumatologist, especially with a lupus diagnosis. They can look at the full picture of lab results to figure out what's driving it.

Regular blood work is a key part of managing lupus, as one MyLupusTeam member put it: *"You definitely need blood tests to keep an eye on what's going on with lupus symptoms to make sure it's not affecting other organs."*

May 11
A MyLupusTeam Member

Kathalina, please talk to your nephrologist about whether it's at a level that warrants treatment.

May 12

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