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Real members of MyLupusTeam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.
June 14
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A MyLupusTeam Member

Thanks for the reply

June 17
A MyLupusTeam Member

A close friend of mine first developed elevated liver enzymes and liver inflammation a few years before her diagnosis, Therese.

June 16
MyLupusTeam

Yes, gallbladder issues can actually be connected to lupus, and for some people, they were part of the path to diagnosis. One MyLupusTeam member shared that they experienced years of severe gallbladder pain without any stones being found — and after eventually being diagnosed with lupus, their doctors believed the Show Full Answer

Yes, gallbladder issues can actually be connected to lupus, and for some people, they were part of the path to diagnosis. One MyLupusTeam member shared that they experienced years of severe gallbladder pain without any stones being found — and after eventually being diagnosed with lupus, their doctors believed the gallbladder problems had been autoimmune all along.

Lupus can, in rare cases, cause gallbladder inflammation even without gallstones. This is known as acute acalculous cholecystitis, and it can sometimes be one of the first signs of lupus. The link between lupus and gallbladder problems is thought to be related to the immune system mistakenly attacking the body. If you're experiencing symptoms like:

- Pain in the upper right abdomen
- Nausea, vomiting, or diarrhea
- Indigestion or swelling

...it's worth discussing these with your rheumatologist or healthcare provider. They may use imaging like ultrasounds or CT scans, along with blood tests, to get a clearer picture of what's going on.

These kinds of symptoms, combined with other lupus indicators, can absolutely help build a fuller diagnostic picture. Always make sure your full symptom history is shared with your care team — nothing is too small to mention!

June 14

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