I'm taking 100 levothyroxine (T4) and 25mcg liothyronine (T3). I split both pills and take both day and night. My body can't convert T4 to T3, so I need liothyronine. My doctor is planning to up the T3 further gradually, because all my tests show the T4 really isn't being converted, but you still need some T4 in your system for other processes. If you take any T3 med, you should take them twice a day, because of it's shorter halflife. I split the T4 pill too, just because the 100 hitting at once possibly caused the heartbeat noise in my right ear. Since, I split it up too, the noise went away. Prior to all this taking two meds, I was on one medication that combined both T4 and T3, and I took it twice a day (Armour Thyroid or NP Thyroid). But, my insurance won't pay for either now, after 20 years doing well on these meds. It went from $20 for a prescription to $170. So now we are trying to get the right mix with two different meds.

Thanks K for the information on your T4 and T3. My GP always read my bloodwork and over the years has said my thyroid was out of wack and would up the dose or lower it. But nothing about my T3. as it seems to stay pretty stationary in the guidelines. Sorry that your insurance has raised your prescription price. Good luck with your doctor inn finding the right mix

K, so you have hypothyroidism? That is what I have and I also take Levothyroxine. Is the T3 also for your hypothyroidism? I only take my thyroid meds first thing in the morning, never several times a day! What is your dosage of your Levothyroxine? It seems my dosage has changed a few times over the years due to my thyroid activity.

I had an odd symptom the other day too. I could hear my heart in my right ear. I assumed it was due to a medication change, and spread the extra T4 (levothyroxine) out with the T3 liothyronine, I was already taking several times a day, and the weird beating/wushing noise subsided. My body can't turn T4 into T3, so possibly the large dose of T4 just set off alarms sitting there in my system.

I certainly am out of breath constantly too. We are planning to move to a one story home soon, and we are hoping this will help.