Yes, both lupus itself and some lupus medications can increase the risk of blood clots. It's a real concern worth understanding and discussing with your doctor.
Lupus and Blood Clots
Lupus can trigger the production of antiphospholipid antibodies, which make blood more likely to clot. Between 33% and 50% of people with lupus Show Full Answer
Yes, both lupus itself and some lupus medications can increase the risk of blood clots. It's a real concern worth understanding and discussing with your doctor.
Lupus and Blood Clots
Lupus can trigger the production of antiphospholipid antibodies, which make blood more likely to clot. Between 33% and 50% of people with lupus have these antibodies, and about half of those people will develop a blood clot at some point.
These clots can occur in serious places, including:
- The lungs
- The brain
- The legs
About 10% of people with lupus develop antiphospholipid syndrome, which is directly linked to these antibodies. Medications and Blood Clot Risk
Some lupus medications can also play a role. Corticosteroids like prednisone can promote plaque buildup in arteries, which raises cardiovascular risk over time.
On the flip side, hydroxychloroquine (Plaquenil) has actually been shown to *reduce* the risk of blood clots by around 49%, so it can be protective.
Some doctors recommend low-dose aspirin for people with lupus who have antiphospholipid antibodies but no prior clot history, as a preventive measure.
It's always worth talking to your rheumatologist about your personal clot risk and whether any adjustments to your treatment plan might help.
September 1