MyLupusTeam

Starting a new treatment can feel both exciting and nerve-wracking — totally normal! Saphnelo (anifrolumab-fnia) is an FDA-approved biologic for moderate to severe lupus (SLE). It works by blocking a signal in the immune system called type 1 interferon, which helps reduce inflammation linked to lupus.

It's given in two ways Show Full Answer

Starting a new treatment can feel both exciting and nerve-wracking — totally normal! Saphnelo (anifrolumab-fnia) is an FDA-approved biologic for moderate to severe lupus (SLE). It works by blocking a signal in the immune system called type 1 interferon, which helps reduce inflammation linked to lupus.

It's given in two ways:
- IV infusion — 300mg every four weeks
- Weekly injection — 120mg under the skin

Since you're starting infusions, here's what MyLupusTeam members want you to know going in:
- Be patient — it can take several months and around four infusions to feel the full benefit
- Stay on schedule — missing infusions can affect how well it works
- Track your symptoms — so you can have informed conversations with your rheumatologist Some common side effects to be aware of include:
- Headache, nausea, fatigue, or dizziness after infusions
- Respiratory infections like colds or bronchitis
- Shingles (herpes zoster)

One important caution — Saphnelo lowers your ability to fight infections. If you feel unwell or develop an infection, contact your care team right away. They may pause treatment until you recover.

Also, avoid live vaccines while on Saphnelo, and let your doctor know about all medications and supplements you take. You've got this! 💪

 AI-generated responses are not a substitute for medical advice. These services are not intended to diagnose, treat, or cure any condition or disease. Always ask your doctor about specific health concerns.

Treatments

Saphnelo