Chances are, you’ve been surprised at some point by a sudden trickle of blood from your nostril. And if you have lupus, you might have wondered if your condition is behind your nosebleeds.
In this article, we’ll explore whether nosebleeds can be a symptom of lupus, discuss other possible causes, and provide practical tips for managing them.
Nosebleeds are generally not considered a common lupus symptom. Rather, nosebleeds are often caused by triggers unrelated to lupus, such as:
That said, some MyLupusTeam members have reported experiencing nosebleeds.
“A few months ago, I started having nosebleeds, especially during lupus flares. I noticed they were worse when my sinuses became dry and inflamed,” one member shared. “To address this, I placed a humidifier on my nightstand while I slept, and it has significantly helped.”
Another member reported, “I have only had one nosebleed in my 20 years of lupus. About 17 years ago, I experienced it for the first time while taking prednisone due to a flare.
“I stopped the bleed and attributed it to the medication. Since then, I haven’t had any nosebleeds.”
Although this member attributed the nosebleed to prednisone, the cause wasn’t confirmed. Research has found that steroid nasal sprays can increase the risk of nosebleeds.
Those experiences illustrate how nosebleeds can vary among people with lupus. Some may attribute occasional nosebleeds to lupus treatments or flare-ups, whereas others may not experience nosebleeds at all.
Factors related to lupus could lead to nosebleeds in some people who have the condition. Inflammation-related sores, certain lupus treatments, or a low platelet count could all play a role.
As an autoimmune disease, lupus can cause inflammation in various parts of your body. Lupus may affect the skin and mucous membranes, and nose and mouth sores can occur.
These nasal ulcers may make you more susceptible to nosebleeds. Sores may occur more often during lupus flares, when symptoms worsen for a period of time.
If you develop sores in your nose, ask your doctor how to manage them. The right treatment depends on what’s causing the sores.
Certain medications used to prevent or treat blood clots, such as anticoagulants and antiplatelet drugs, can increase bleeding risk. This may lead to or worsen nosebleeds.
If a medication may be contributing to your nosebleeds, talk with the healthcare provider who manages it. They can decide whether your treatment needs to be changed. Don’t reduce your dose or stop taking a blood thinner without medical guidance.
Platelets are blood cells that help blood clot and stop bleeding. Too few platelets can increase bleeding risk. In lupus, your immune system can attack and destroy platelets, leading to thrombocytopenia (low platelet count).
According to the Hospital for Special Surgery, up to 25 percent of people with systemic lupus erythematosus (SLE), the most common type of lupus, may develop thrombocytopenia.
Some medications can also cause thrombocytopenia. For example, statins, which are used to lower cholesterol, and some nonsteroidal anti-inflammatory drugs (NSAIDs) can lower platelet counts.
NSAIDs such as naproxen and ibuprofen may be used to manage pain and inflammation in people with lupus.
A low platelet count can cause easy bruising and bleeding, including nosebleeds.
Treatment for lupus-related thrombocytopenia depends on how low your platelet count is, whether you have bleeding, and how severe your symptoms are. Treatment may include corticosteroids along with other medicines.
Many factors can set off a nosebleed. Knowing about these triggers can help you determine whether your nosebleeds are related to lupus. Common causes of nosebleeds in people with and without lupus include:

You can take several steps to stop an active nosebleed. In addition, several strategies can help reduce your risk of getting nosebleeds.
Dealing with a nosebleed can be a bit scary, but a simple plan can help you manage it effectively. Follow these steps to treat a nosebleed:
After your nose stops bleeding, proceed with caution. To prevent the nosebleed from coming back, don’t bend down or blow or pick your nose for several hours.
Whether or not your nosebleeds are related to lupus, you can take several measures to help prevent them:
Although most nosebleeds can be managed at home, some require emergency care. Seek emergency medical care if:
Contact your healthcare provider if:
Remember, it’s always better to seek medical advice if you’re unsure or concerned about your symptoms.
Get updates directly to your inbox.
Become a member to get even more
This is a member-feature!
Sign up for free to view article comments.
Can you test positive for Lupus one year then test negative?
We'd love to hear from you! Please share your name and email to post and read comments.
You'll also get the latest articles directly to your inbox.