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Real members of MyLupusTeam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.
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New Milford, CT
March 31, 2025
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Yes, certain lupus medications can cause weight gain. Corticosteroids, particularly prednisone and methylprednisolone, are the most common culprits. The likelihood of gaining weight increases with higher doses and longer treatment duration. Many MyLupusTeam members have shared their experiences with steroid-related weight Show Full Answer

Yes, certain lupus medications can cause weight gain. Corticosteroids, particularly prednisone and methylprednisolone, are the most common culprits. The likelihood of gaining weight increases with higher doses and longer treatment duration. Many MyLupusTeam members have shared their experiences with steroid-related weight gain, with some reporting gains of up to 50 pounds. Beyond medication effects, lupus itself can contribute to weight changes through several mechanisms. These include fatigue and joint pain that make exercise difficult, thyroid problems that are common with lupus, and vitamin D deficiency. If you're concerned about weight gain, it's important to discuss this with your healthcare provider, who can help adjust your treatment plan or suggest management strategies while still keeping your lupus symptoms under control.

March 31, 2025

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Puyallup, WA