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Real members of MyLupusTeam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.
June 7, 2025
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MyLupusTeam

Yes, feeling flu-like symptoms and extreme fatigue after Benlysta treatments is a common experience. Some common side effects include:

• Fatigue
• Muscle pain
• Nausea
• Headache Many MyLupusTeam members have shared similar experiences. Some report being bedridden for two days after infusions and feeling weak for up to a Show Full Answer

Yes, feeling flu-like symptoms and extreme fatigue after Benlysta treatments is a common experience. Some common side effects include:

• Fatigue
• Muscle pain
• Nausea
• Headache Many MyLupusTeam members have shared similar experiences. Some report being bedridden for two days after infusions and feeling weak for up to a week afterward. While injections often cause milder symptoms, they can still cause fatigue and other side effects on a weekly basis.

The good news is that despite these side effects, many members report seeing positive results in their lupus symptoms over time, including improvements in skin and joint conditions. If these side effects are severely impacting your quality of life, discuss them with your healthcare provider - they may be able to adjust your treatment plan.

June 7, 2025

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