How does lupus affect the GI tract in older adults, particularly with symptoms like vomiting and diarrhea (lupus enteritis)?
Lupus can cause inflammation throughout your digestive system, and lupus enteritis specifically refers to inflammation of the bowel wall. This can lead to the severe symptoms you're experiencing - Show Full Answer
How does lupus affect the GI tract in older adults, particularly with symptoms like vomiting and diarrhea (lupus enteritis)?
Lupus can cause inflammation throughout your digestive system, and lupus enteritis specifically refers to inflammation of the bowel wall. This can lead to the severe symptoms you're experiencing - vomiting and explosive diarrhea.
Between 40-60% of people with lupus will experience some type of gastrointestinal issue. The inflammation can affect:
- The esophagus
- Intestines
- Nervous system (which affects digestive regularity)
- Pancreas
- Liver
- Other abdominal areas
Lupus enteritis and related inflammatory conditions like vasculitis (inflammation of intestinal blood vessels) can cause:
- Severe abdominal pain
- Nausea and vomiting
- Diarrhea
- Bloating
- Constipation alternating with diarrhea
These symptoms can be particularly challenging because they may come from lupus itself, lupus medications (like NSAIDs or steroids), or related infections. Lupus and certain treatments like steroids and immunosuppressive drugs can increase infection risk, which may also cause severe GI symptoms.
It's crucial to work closely with your doctor to determine if this is lupus enteritis or another cause, as this will guide the right treatment approach. They can help diagnose the underlying inflammation or infection and adjust your treatment plan accordingly.
November 29, 2025
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