I was worse when on gabapentin, so dr switched to lyrica and it still happened. I have been off of it now most of the year and my bouts are less frequent.
December 22, 2025
Are you experiencing hand jerks or involuntary movements while taking Lyrica?
While the search results don't specifically mention Lyrica (pregabalin), hand tremors and jerking movements can happen with lupus for several reasons. These involuntary movements can make it difficult to hold objects and may worsen during Show Full Answer
Are you experiencing hand jerks or involuntary movements while taking Lyrica?
While the search results don't specifically mention Lyrica (pregabalin), hand tremors and jerking movements can happen with lupus for several reasons. These involuntary movements can make it difficult to hold objects and may worsen during flare-ups.
Several MyLupusTeam members have shared similar experiences. One member described having to use two hands to hold something due to tremors, while another said their hand would tremble and lose grip, causing them to drop things.
Hand jerks and tremors in people with lupus can be caused by:
- Lupus affecting the nervous system
- Side effects from certain medications
- Thyroid issues (which are more common in people with lupus)
Some lupus medications that can cause tremors or involuntary movements include corticosteroids, immunosuppressants, and hydroxychloroquine. Similar medications like gabapentin have been reported to cause muscle twitching in some members, even though they're typically prescribed to reduce unwanted movements.
It's important to talk with your doctor about these symptoms, especially since they're affecting your daily activities. Don't stop taking any medication without consulting your healthcare provider first, as stopping suddenly can cause withdrawal symptoms. Your doctor can help determine if the jerking is related to your medication and explore alternative treatments if needed.
December 22, 2025
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